Saving .tga

Okay so I have new models out but I can't seem to get them skinned properly. In fact, I can't even seems to get existing units skinned.

Here's my problem:

I open a .tga.dds file with ImageReady in Photoshop. Then I make no changes to it (so as to eliminate a variable) then I resave the file as a 32 bit with the alpha thing turned on .tga. When I load the game, the skin is all messed up. It looks to me as if there occurred a problem with the UV map somehow...

Can someone PLEASE help me with this one? How are you saving your newly made skins? I need details...

Thanks in advance.

This may be a stupid question, but why ImageReady instead of Photoshop?

Did you choose No when asked if you wanted to use existing mipmaps, and then generate new ones when saving? Did you choose DXT5 when saving?