I would actually almost encourage the opposite, i.e., mainly use regional troops against others of the same culture. If you think about the speed of communications at the time and the distances involved, the majority of rivalries would be local, and in a largely monarchical / oligarchical society there would also be pretenders, the disenfranchised or sidelined heirs for an greater power to use as an excuse for intervening.Originally Posted by Visitor13
Some factions might be expected to be naturally fissiparous (oh, I love that word), for instance Rome (think of the Social War, and revolts of the Italian allies during the Punic wars) and the Seleucids (breaking up into various mini-kingdoms and a rump state). Others, including most of the barbarians plus the KH, represent federations where political tensions may also come to the fore. And a further set (e.g., Pahlava, Ptolemaioi, Carthage in Spain, Epirus and Rome in the mid-later game) represent a ruling class imposing themselves on subject people of a different cultures - depending on the regions where the conflicts happen - and those subject peoples might be more than happy to support an invader on the assumption they might achieve more autonomy under new rulers.
So all in I'd positively recommend throwing auxiliaries of any stripe against troops of their own culture, as an abstraction of all the above.
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