You are running some program that the copy protection deems bad, such as something that could be used to crack the copy protection (fat lot of good that did), or you have done so earlier since restarting Windows. The first thing you should do is restart Windows and see if it works then. If not, check which programs are automatically started when you do.
If the message disappears but the game still crashes, you should try all the suggestions in the installation validation sticky.
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