It's gone into the irrevocable CTD that killed my last game again. This time it's Pella that's the problem, just had a crash on my spy trying to look into the settlement.
Restart...right now I'm running a full virus-scan before I reinstall the game; all those long periods of time with it disabled might have allowed something to take hold (I disconnect the internet while I'm playing too, so it's not exposed at the time).
Bookmarks