I might be wrong but one of the causes of the macedon problems could be their possession of Mytilene. There usually is an almost full stack lurking around there doing nothing but cost them money, where they could be of better use in their mainland possessions. The AI seems to think it's necessary to garrison that city heavily (probably because of the strong Pergamon rebel garrison) but doesn't attack it. Moreover, it usually takes quite a while for anyone else to take Pergamon, so maybe removing the landbridge to Pergamon, thus turning Mytilene into an isolated island might help. The KH in comparison don't garrison Rhodes that strongly.