I have seen often here people claim they abandoned their campaigns once due to a CTD. Well, I just had a CTD in my Romani campaign for the second time, but to me it isn't a big deal at all compared to a corrupt save file or the likes. I always save often and turn the autosave on so CTD's hardly affect my game to the point I would rather give up from them.

So what's the big deal? Just save often and when the CTD comes you will just have to remake some few moves, that's it.