Sounds like somebody needs a windows re-install!
In that case - SAVE YOUR SAVE GAME FILES TO A DISK!!!!!!!!! (CD NOWADAYS) Then put them back into the proper folders after you re-install windows, every single program you have, and necessary updates
If you're really lucky, and I mean really lucky, you may even have bad sectors on your hard drive!
If that's what has happened, you can try to format it; but more than likely is $$$ time.
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