Sadly guys, your best bet may be to e-mail CA's customer support.

The fact you can run RTI but not the grand campaign leads me to believe it is either a file error or a error with the disk.

The only way to know if your disk is damaged that I know of is the old fashioned way. Which is to copy and paste the entire contents of the grand campaign map to another file folder and see if they copy.

If that fails you, I'd say your two hopes are either a reinstall or hope the patch next week with graphical fixes addresses your issue.