Okay

In turn one attack Pahlava first with the Persian Archers or the Babylonian Infantry, this is to keep Pontos, Baktria and Hayasdan allied. Then gather ALL troops you have spare and send them to Antiocheia-Margiane to prepare the Counter-Attack on the Pahlava who have Asaak by now.
In turn 1 replace GovIII with GovIV and recruit a merc general in Marakanda.

Then take Nisa to take out there recruitment center and raze everything or try to hold it.
In the west blitz Sidon and Hierosolymna and defend it for the time being. Then it's up to you what you do next, your enemies will be pacified for at least a decade.