Quite literally, alcohol is an intoxicant; cannabis is not.

The word intoxicant is derived from the Latin noun, toxicum, meaning: “a poison.” It’s an appropriate description for booze. Alcohol is toxic to healthy cells and organs, a side-effect that results in some 35,000 deaths per year. Ethanol, the psychoactive ingredient in booze, is carcinogenic following its initial metabolization, which is why even moderate drinking is positively associated with increased incidences of various types of cancer. Heavy alcohol consumption can depress the central nervous system — inducing unconsciousness, coma, and death — and is strongly associated with increased risks of injury (Booze plays a role in about 41,000 fatal accidents per year, according to the U.S. Centers for Disease Control.) and acts of violence. In fact, according to the federal Bureau of Justice Crime Statistics, alcohol consumption plays a role in approximately one million violent crimes annually.

By contrast, the active compounds in marijuana, known as cannabinoids, are remarkably non-toxic and actually mimic chemicals naturally produced by the body, so-called endocannabinoids, that are vital for maintaining one’s proper health. Unlike alcohol, marijuana is incapable of causing fatal overdose — cannabinoids do not act upon the brain stem — and its use is inversely associated with aggression and injury. Finally, lifetime use of cannabis is not associated with increased risk of mortality or various types of cancer — including lung cancer — and may even reduce such risk.