Not really. American Indians generally abandoned their native weapons for muskets and rifles as quickly as they could get ahold of them. In fact, one of the keys to Britain finally pacifying the Eastern Indians at the end of the French and Indian War was their ability to almost completely deny the Indians access to firearms once the French had been kicked out of North America. Without firearms, most Indian tribes were unwilling or unable to sustain any sort of effective operations against the British-Amerian colonies.
In battle, American Indians only defeated European infantry when they either significantly outnumbered the Europeans or they were able to catch them in a close range ambush where massed fire was rendered useless. In any sort of standup fight with relatively even numbers, European infantry invariable came off the better. That the Indian wars continued as long as they did prior to the Revoluation had more to do with the general unwillingness or inability of the European powers to deploy large numbers of troops to the North American theater and the extreme inhospitability of the North American terrain at the time to European style campaigning. The game significantly exagerates both the effectiveness of organic Indian weaponry and the Indian's ability to resist trained military formations on the battlefield.
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