It's impossible to answer this question without knowing what kind of computer you have, eh? I have a 4 year old iMac and run M2TW mods (including our internal build) on it with no problem- but the larger the battle, the more lag, of course. My solution is large unit size, as opposed to huge, and that solves everything for me- I can max out all the graphics settings just as long as I keep the unit size at large. RAM upgrades can also help a lot.
I can't and/or won't give away anything about EB2 here, but we have of course observed some of the very script-heavy mods like DLV and SS, and have tried to mind some less complex solutions.
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