Copper bottomed guarantees don't exist in science (nor as far as I'm concerned in any other sphere of human knowledge). Any scientific result is only ever a statistical best fit, with an associated level of uncertainty. It is unfortunate that due to the generally extremely low levels of such uncertainties which make it into most visible applications of science that this fact has been largely forgotten among the public, and thus people talk about a thing being "scientifically proven" as though that means it is proven conclusively beyond all doubt.
In any scientific experiment, we can never be better than "almost certain" that it will not destroy the Universe. The best we can do is to examine whether it has been done before; in the case of the LHC, we can observe that the type of collisions planned in the detector are equivalent in energy and particle type to those that occur between cosmic rays and the atmosphere. We can then consider the typical cosmic ray flux in our area of space (a lot), the total effective surface area of the atmosphere (big) and how long these collisions have been going on for (a long time) to conclude that if collisions at these energies do produce anything nasty, it is vanishingly unlikely.
Ultimately though, there are no guarantees. The question is whether the risk of experiments with unknown physics having nasty consequences outweighs the negative consequences (and there will surely be negative consequences) of suppressing all future research. After all the LHC is not the only experiment being run to look for previously unknown physics - by definition the only experiments which can find new physics are those where we are not sure beforehand what the results will be. Has our society reached such a level of technology that it is possible for us to stagnate indefinitely, and simply sustain our current standard of living on what technology we currently have? And if so, is the status quo really so fantastic that no attempt to improve it would ever be worth the risk?
And as others have observed, it has often been the case that research performed purely to advance human knowledge has led to applications that would likely not have come about otherwise. The most obvious example I can think of is electricity: Were the pioneers of electromagnetism supposed to have been able to foresee all of its future applications before they started mucking around with magnets and bits of wire? If we are interested only in the potential applications of science, then past experience suggests that at least some effort should be put into trying to make inferences about the underlying principles of science rather than only going after the obvious applications of what we already know.
As to the question of the results - the LHC has only been performing actual experiments to look for new physics since the end of March:
One could legitimately argue about whether the results, if they are close to our expectations, will be worth the massive expense. I for one heartily wish whoever was responsible could have refrained from attaching the ridiculously overblown and controversy-seeking title "the God Particle" to what is actually just a fairly mundane test of the Standard Model - the view among many of my colleagues seems to be that simply finding the Higgs boson in the expected energy range, and nothing else, would be a pretty disappointing outcome. It is certainly premature to state however that the machine has achieved nothing - the experiment hasn't been done yet.Geneva, 30 March 2010. Beams collided at 7 TeV in the LHC at 13:06 CEST, marking the start of the LHC research programme.
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CERN will run the LHC for 18-24 months with the objective of delivering enough data to the experiments to make significant advances across a wide range of physics channels. As soon as they have "re-discovered" the known Standard Model particles, a necessary precursor to looking for new physics, the LHC experiments will start the systematic search for the Higgs boson.
As for the original subject of the thread, I personally think that having a "brain hat" which would let me control the exact state of my own mind, rather than having it dictated to me by external factors and my own body chemistry, would be awesome. I think it would be at least worth considering whether the benefits might outweigh the obvious risk of someone else getting their hands on the controls.
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