Mana Clash is the highest damaging attack in the game.
Have Wynne learn it, set her tactics to use it on the nearest Mage with >75% mana... pretty much guaranteed a one-shot if they're not a boss-level mob, even on higher difficulties.
It's a little bit cheap, but then again, so's being one-shotted by a Mage's fireball... if they're going to kill me instantly, I'll strike back in kind. :3
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