Yes.

I have a half-finished "Historical campaign" based on The Italian Wars (1495-1525).

Only problem is the MTW AI is extremely poor in this respect and once you've positioned the units historically as soon as you start a battel the AI moves everything - so the "Historical Campaign" becomes a meaningless misnomer.

Best advice, if your new to all this, is to carefully study the parameters in the existing "Historical Campaigns" and try not to deviate too far from the paramters defined there.