Well, in my Ptolemaic campaign, my army in (western) Anatolia is based on Thureophoroi as the main force. This is, of course, because I don't have much of a choice: no phalangites are available for training there (at least not yet). I can't say how that's working out, though, as they haven't been put to any real test yet. However, based on the performance of my "marines", that is my army of a few thureophoroi supported by light cav and archers, it should work well enough.
Elsewhere I mostly use them on the flanks which seems to be standard practice around here.
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