Nope.

I gave them 900 000 denari, and gave them the trait "craftsman caesar".
Also I boosted their population, and made it that way that all their starter units had 3 gold chevron.
Finally, I made some negative modding on Egypt.

If they coudn`t win after all that, then their really incompetent.

But I have read that you only have to change the traits to make the seleucids win.