I'd like to assume that this wasn't a loaded question, an exercise in coat-trailing if you will. Any reply here will have to be carefully worded indeed to avoid giving ammunition to the gamers who want to think the worst, no matter what.
So, do people mod the game? Yes, of course they do. But not in the way that you mean. BI, for example, has reached a state where it works as intended, sort of. What follows after that is an exercise in 'modding' the systems until they produce the results we want. That might be data modding, or it might be new code. The whole process is often an exercise in large leaps and then many iterative steps towards a finished result. We do have a semi-secret advantage over the modders, of course, in that we can work on data and code; they are limited to the data.
But as to whether people mod the finished game and then play, I'd think it would be very unusual. I don't, and I doubt that many others do either. There are two reasons. Builds have to be rigorously tracked for development purposes, and multiple mods 'muddying the waters' when it comes to reporting bugs, features and what have you would just make our lives more difficult. Secondly, we consider it finished; by definition what get's published is as close to what we want as can be achieved within time, budget and publisher's constraints.
Obviously, when we start working on an expansion, the first thing to do is start modding... then new code... more modding... more code... ad infinitum. Or until the grown ups tell us to stop.
ps: Harun, you're wrong.

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