I agree partly that Western 'things' had some role in the unrest of the Muslim world.

However, it is all fairly recent:

2003 - Invasion of Iraq: Further Polarized both worlds

1980's - US and Soviet meddling in Afghanistan: Led to a US supported Afghani mujahadeen, of which Al Qaeda split off from years later.

1948 (or is it 47?) - Creation of Israel: You know what this caused: wars, hatred, etc...

1918 - Treaty of Versailles: Dissolved the Ottoman Empire and destroyed last glimpse of Muslim unity.

1600-1800: Gradual Colonization of Muslim lands: If you really want to go this far back, here was the first real time that European power eclipsed Muslim power.

Before this the two worlds lived fairly isolated from each other, aside from the clashes on the borders.

The Crusades were probably brief interruptions, and the Reconquista was so complete that the Muslim Spanish populace had been reduced from millions to 20 some in years...