Well, we'll soon see. I am not sure the core campaign will be heavily scripted - it would certainly be an innovation if it were. (It should not be confused with the linked battles that Brian Blessed has done the voice work for.)
But I think the map and victory conditions will dictate that the only way for Alexander to go is east. Rather like how the Vikings in Viking Invasion could only go to the UK. Beyond that, I expect the Macedonian player will have all the freedom you normally enjoy in a TW campaign. As I say, I normally dislike blitz games - I'm a turtle - but this is one where doing a blitz is entirely historical and doing as well as the historical outcome could be a good challenge in a game. Rather like replicating the fall of France in 1940 in a wargame.
Not sure about other factions not being playable. If true, it would be disappointing although I suspect they - at least the Persians - might play out rather like the Japanese in Mongol Invasion. Some horrendous battles to begin with and then, if you are successful, it's game over in a few turns. Not a very interesting strategic situation.
Bookmarks