Second time I've seen this now. Before I reinstalled and after a reinstall. The first time I can't remember which faction I was. This time I had started a campaign as the papacy and I had been playing for about an hour and went to save. Hit escape, the screen went black and the background music continued playing, and that's it. I waited about 3 minutes then realising that "it wasn't going to happen" did a ctrl alt del and saw the usual error message, which unfortunately I didn't bother to check as it was getting late!

Next time this occurs I'll note down the error. Anyone else had this exact problem? And I don't mean regular CTD's before starting a campaign, What I am referring to is a crash when you hit escape to try to go to the menu.