Ran it on medium setting and ran very good.
I was really surprised.

Tutorial Battle: was slightly pointless IMO but on the other hand I'm a TW vet so it is useless for us

Pavia: Awesome battles this.
Just hearing the german accent is just awesome.
Seeing the cavalry charge your landsknechter was slightly fun but the real fun was when you see your zweihander in action.
They are just as cool as we had imagine.
Also the first time I saw some finishing moves was from these guys.
Needless to say they can turn a unit into a bloody pile of corpses very fast.

Agincourt: Oh this battles was a bit tough on my computer but still fine.
The french infantry almost destroyed me but then I noticed that I had billmen ready so I was saved.

The music is great and so is the sound.
Graphics even on Medium looks wonderful.
The animations are so much better.
The AI is scripted like hell but in times where I felt that it could act on it's own I felt it was better.
Movement and kill-rates are fine now too.
Gotta remember that your troops have alot of bonuses compared to the enemy and still they lasted longer then in RTW.

I say M2TW is looking very very good

Some screens from Pavia