Well this is what i'd to if i was France

Expansion
Take Bordeux, Rennes and possibly Bern, or Zaragoza. Taking Bordeux will provide a solid defense to your rear or your frontline, and Rennes will stop English expanding too far, so if you take them out of Caen, they will prove not to be a problem.

Trade and Diplomacy
Seens as though you a fairly near central Italy, it might be a good idea to either send a diplomat or constance down there to get some trade rights or allies, then she will have full charm and you can consider stealing a general.

Papal Favour
I would suggest gifting the Papal States a town, possibly Rennes or Bern, somewhere where an attack is likely, Bern will almost certainly be assaulted by the Milanesse.

War
The factions you will be at war with are likely to be England, Portugal and Milan, and possibly Spain, just fortify your borders and crush them and you will be fine.