The plague is a disaster in this game, nothing like how it was in RTW. One city got the plague randomly, just as the spanish were invading. To refortify my positions along the border I started moving troops around and two other cities got it. Now I'm receiving losses of nearly 200+ troops per turn and thousands of citizens. The first battle I successfully defended against the Spanish, receiving heavy casualties. Now the spanish troops get the plague after coming in contact with my infected troops and start spreading it on their home front and along the country side.

In a nut shell the plague is everywhere and everyone is dieing. Has anyone else noticed the strong effects of the plague in M2TW vs. previous total war's?