I've had it hit around 135 both times I've played that far... that's year 1350... which is cool, since the real plague hit Europe around 1347. Playing as Spain and holding 40 territories, it killed off 45000 citizens and 1500 soldiers and 10 family members on one turn. That was at its peak, but it was always pretty bad. I also had the experience of gaining money from it, rather than losing, since it gets rid of all that squalor in cities that I had built up as economic powerhouses... no beggars in the streets when you can just take your dead neighbours house and job, I guess.
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