In 1080 the "Swiss" were truely "Germans". They were part of the Imperium Romanum (later called Sacrum Imperium Romanum = HRE). They counted themselves among the "upper German countries" (oberdeutsche Lande) maybe till the war of 1499. From then on the Swiss Confederation was really independent in fact but became a true state of its own first in 1648 with the peace of Münster and Osnabrück.
Because there are no eras in M2TW it would be another unhistoric touch (added to the many existing) to make the Confederation a faction too early on. But it would indeed be very nice to field the mighty confederate armies of the late 15th century!
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