The problem I usually have is the opposite -- 1 ppi on document open, but 300pt text shows up as very tiny hen scratches. CS2 seems to have horrendous default settings for DPI and pixel aspect ratio when opening documents. Hopefully this is an annoyance Adobe will fix with CS3 (not that I'll know for a while).
At any rate, LEN and Cambyses are definitely right, it's all down to the dpi/ppi setting you use.
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