I agree with what Diotavelli says...
In my last campaign, i played the Scots and managed to maintain alliances with Spain, France and Papal states throughout the campaign and with Russia till they were wiped out by the Mongols. Sicily was also an ally for 100+ turns who then blockaded a port and broke the alliance... Even when i finished the campaign (barely managed to get the 45 cities required) i was at war only with Sicily, Denmark (perenialy excommed), Turks and Egypt.
Bookmarks