Centurio Nixalsverdrus: a basic rule of thumb is, if you can play the latest issue in the series (smoothly) at full settings; the next one will be possible (with low settings). So if you've got M2TW you can already test that bit.
EDIT: In all likelihood, you still will have to upgrade your GFX card to something more powerful, though. Since this kind of game mainly seems to consume raw memory & power rather than sophistication; I'd say you should look for a card with a healthy dosage of onboard RAM; of the newer types.
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