I'm playing M/M (I'm not hardcore enough to try anything more difficult) and so far I'm actually finding Baktria quite easy. I took Kophen first, and then, seeing that I was either going to attack or be attacked by AS, I went and too Alexandreia-Ariana, consolidated, and went on to take Prophthasia and Alexandropolis (although the AS didn't want to go easy on Alexandropolis). After that, I've just taken Opiana, so that should give me some nice Indo-Greek units. I'm planning on taking either Taksashila or Patala next, consolidate in India, then go after Pahlava and the AS.

So far Pahlava hasn't attacked me yet, although they have just sent a small force into my lands which I should be easily able to take care of. Those treacherous Easterns won't get away with this!