The big thing you'll not have without the script is AI government placements. Without the script on, they would get a government placed. They will then take a long time to build one and if they ever do, it will be inappropriate for the region since the homeland/subjugation/alliance buildings will have been placed for your faction. As a result, they won't be able to recruit the appropriate units in any faction they acquire through conquest.

Then this is the mentioned things of, all but 2 factions will go broke on turn 2 and will never recover. And if they do get money, they will deplete the population of their town quite quickly.