I'm not skilled enough to use all that hotkeys. :P I only use a few hotkeys:

P -- Pause
N -- Normal Speed
T -- Triple Speed
G -- Group
Alt-click -- Melee attack

That's about all I use. I normally issue orders in pause, and for orders like Fire At Will or Guard Mode or special abilities, I just click on the button. Shockingly primitive, I know, but thank the gods (or at least CA) for the Pause button.