The problem with Monoculture at the most fundamental level is even within Native Ethnic groups there are usually more than 1 distinct cultural group and to implement a monoculture you will need to suppress the other cultural identities - this is entirely possible and many cultures have dabbled in it (the Kingdom of England's suppression of Welsh culture for example) however the methods aren't often very "tasteful" and the results can backfire spectacularly...
In the other thread you used Syria as an example of a failed Multicultural state - id argue in fact the opposite - Assad's regime were attempting to instil a monoculture state by suppressing the rival cultural group (the Sunni Muslims in this case) which in combination with their Authoritarian methods lead to the uprisings and the now brutal civil war... ironically should the Sunnis win they will probably try the same thing in reverse...
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