I tend to avoid Antwerp. As the English, it ends up being the very frontier of my continental holdings and Denmark always attacks it.

But I have to defend Baghdad in here. As the English, I always take Baghdad. It has great resources and is big. Plus, it ends up becoming a tripwire. The Mongols and Timurids tend to spawn there in my games. With ballista/cannon towers and stakes, I can hold Baghdad fairly easy. Even if I can't, I can bleed the Mongols/Timurids and stall them enough to get my other armies over there ASAP. That ends up protecting the crown jewels of Outremer which are Jerusalem and Antioch.

And my favorite reason to hold Baghdad is so I can keep a governor there and recruit elephant mercs.