Well to build your endurance run in intervals; run as hard as you can for one minute then walk for one minute, repeat. Helps a lot with breathing too, as a former smoker it was much harder for me to get my lungs in shape than my legs. Gradually stretch to running 2 minute and walking 1, then run 3, etc. You'll be doing 10ks in no time.
Intervals work fine for knocking out headaches too because your heart rate stays up, thus gradually altering the blood flow pattern that's typically causing the headache.
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