Happy Farm? Never even heard of that one.
Brain Age? Influential? Don't make me laugh.
Metal Gear Solid 2? Sure, if you think confusing plotlines about the Illuminati is influential. Take out the "Solid 2" part and then it would be certainly influential to gaming.
Portal? Only if you count internet memes as influential.
World of Warcraft? Replace that with Ultima Online and I'll agree.
Guitar Hero? GH is merely the logical evolution of Dance Dance Revolution.
No Super Mario Bros or Pong or Zork? All three influenced gaming on their platforms (Consoles, Arcades, and Computers respectively) more than the entire list combined.
Man, this list fails in so many ways. It was clearly written by someone who doesn't know gaming history.
EDIT: I'd also like to mention that while UO was the first successful graphical MMORPG (Meridian 59 never enjoyed the popularity of UO), GemStone III was the first successful fantasy MMORPG, six years before UO. UO was also the first MMORPG to include optional expansion packs.
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