I think it would work fine on all conventional FPS games with one small modication: splitting mouselook off from weapon aiming. If mouselook was controlled by the headset while the aiming was still contolled by the mouse, you could aim someplace other than the middle of the screen, thus allowing you to peek around a corner with your head and pop off a few shots while most of the rest of you remains in cover. Movement would still be controlled by the keyboard.