Boss battles are fine, as long as the game includes Quicksave. Which every game should. Checkpoint saving is the spawn of the (console) devil.
Hardest boss ever: First assassin in Baldur's Gate, the one at the 'tower' tavern place where you meet Khalid and Jahiera. He is scripted to start the battle with a triple magic missile on the player character. Given that most people were level 1 when they got there, they never had enough hps to survive the spell.
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