Thats true. Like sad earlier by Cbvani germs and Smalpox surely decimetad the native Amercans.
About why they didn't make Iron weapons I heard of theories that clam it also had Geograpical reasons - since the american continent is somewhat divided by different climatical zones use of Animals and technologies could only spread at a slower rate if at all.(use of metals agriculture, keeping livestock and other Animals and writing didn't form in Europe but rather in the Middle east and later spread in Eurasia where it was perfected

) Beside they believed obsidian to be effective enough so they didn't look for new Materials.
Tha fact that the natives weren't united against the "conquerers" also had an inpact - some sorcues mention that by the Time the Incas rebelled every Conquiztador was protected by 2-3 warriors from Native tribes allied to them.
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