With regard to the Drake Equation, courtesy of XKCD;
The time required to travel to a different galaxy is so inconceivably great that pondering civilizations in other galaxies will always be purely academic.
The nearest non-dwarf galaxy is two million light years away. Light takes eight minutes to travel the 93 million miles from the sun to earth. Now imagine not eight minutes but two million years traveling at the absolute fastest anything in this universe can travel to reach just the closest spiral galaxy.
Intelligent life out there somewhere? Maybe. But I hope we never find any - or rather that none ever finds us.
As for UFOs? Bah - we could detect any foreign object in our solar system easily enough to find any spaceship coming at us.
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