No problems here, but maybe it's because I grew up playing combat flight sims. I got used to the weird disconnects in "padlock" view systems, where the direction you look isn't always the direction you're moving. A typical FPS is nothing, compared to that, as long as the frame rate is high enough not to be jerky. I had to stop playing Bioshock when I first tried it, until I got a better video card so I wasn't wasting ammo on missed shots.

I do occasionally get disoriented in some types of games where you can't always tell what direction is up. There was a space game like that a while back... can't remember the name... but one segment had you flying inside these big structures where you could move in any direction, and it got confusing at times. But that's more a case of getting temporarily lost and having to regain one's bearings, not actual physical queasiness.