I've never been rendered unwell by a videogame of any description, though I have been playing them (including FPS) for about half of my life. Curiously the closest thing to nausea I have experienced (a sense of disorientation) occurred with a third-person game, I seem to be in a minority in that I find a first-person perspective intrinsically more intuitive, especially compared to "over-the-shoulder" camera.

Antagonist