They were large, displacing in the region of 2000 tons. Considering galleons were a ship type built purposefully for war, I wouldn't say they were entirely useless, even though they wouldn't really stand up to a ship of the line individually. Which is why they ceased to be used by navies in the early XVIII century as main warships.
Yet the Manila Galleons continued until 1815, starting in 1565 which is a lot more than any other ship type in history, meaning they were good at doing what they did.
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