Let me try to sort out "Greek colonies" and what that meant.
First colonization was when the Dorians invaded, and many peoples left from mainland Greece to establish colonies in the opposite Anatolian coast.
The colonization of the Mediterranean coast prior to the Peloponnesean war is reffered to "2nd Colonization" period.
The colonization of the vast fragmented Empire that Megas Alexandros bequeathed to us, from the Red Sea to Alexandreia Oxeiane, to Patalene in the mouth of Indus river, is refered to as the "3rd colonization". It started during the campaign of Alexandros and ended around 200 BCE, with the possible exception of the new cities founded by the IndoGreeks in present day Punjab and up to "Mathura ton Theon" (Mathura of the Gods) in India which was their largest continuous territorial expansion, during the reign of King Menadros.
This is the most basic explanation of the 3 greek colonizing periods I can give. Anything more and my answer would fill pages.
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