1. Samnites take over Italy.
The Samnites most likely wouldn't have had the influence and reach of Rome, but if I remember correctly they did have a good military along similar lines to the early Roman army, and Rome was the main thing standing in their way. Assuming that none of the other powerful Italian factions took Rome's place and slapped them around a bit, the Samnites and their buddies would've been the guys in charge.
2. Pyrrhus and friends invade.
He wanted to emulate Alexander the Great, but in the west. Due to the Samnites position I'm not so sure that they would've been able to muster the resources that Rome did against the Epeirots, thus allowing Pyrrhus to slap them around get a good base in Italy. Then he'd probably try to take over all of Italy and make forays into Celtic lands.
3. Celts get pissed off.
The Celts would respond by raiding the Epeirots' new territory and by helping out any little Italian groups that tried to free themselves of Epeirot rule, but then eventually they'd go back to beating on each other some more.
4. Carthage takes over Iberia, since no one but the Iberians care.
5. Carthage and Epeiros eventually get into a big fight over Sicily.
Both sides butcher each other over land, Carthage gets some victories at sea. Eventually Carthage gets Sicily.
6. Carthage makes a pass at Italy, but it gets its ass handed to it in this venture.
7. Carthage goes for Epeiros itself, gets some Illyrians to help it out, and smashes up some cities, but is eventually pushed back.
8.Wars go on for a while, Carthage has problems keeping Iberia under control, but eventually they get support from Gaul and make a naval invasion of Italy. Epeiros begins to fall.
9.Eperios gives up and never again rises to greatness.
10. Carthage tries to subdue the continually rebellious Iberians, the Numidians, and the Gauls. Doesn't work. Carthage doesn't have the military might to keep expanding against numerous people who would rather not be under Carthaginian rule.
11.Some of the Gallic tribes unite into a feudal confederacy, allowing them to gain control over Gaul and they go after Britain and the weakening Carthage.
12.Hordes from the steppes migrate into Europe and take over the eastern part. Greece and Italy are nearly overrun. Carthage manages to recover most of its losses, and Carthaginian elephants prove very useful against the heavy steppe cavalry. Macedon also holds out, but becomes too weak to fend off the other Greek powers.
13.The invaders turn on Gaul, and ravage the area but are eventually stopped.
14.Parthia has skirmishes with the remaining Greek Empires, but doesn't make it to the Mediterranean.
15.The Sassanids take over where their Parthian predecessors left off, crushing all opposition in central Asia and getting themselves into a bloody war with the Egyptian dynasty. They take over many areas of Greece and eastern Europe.
16.Egypt and North Arabia fall to the Muslims.
17.Carthage gets taken out by the Muslims, Iberia and Italy become fully independent again, but many aspects of Carthaginian culture have been incorporated into their socieities.
18.The Muslims take Iberia, but the Gauls do not give way to them.
19.The Sassanians hold back the Muslims in central Asia.
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